Memorial Sloan-Kettering Cancer Center Computational Biologist I in New York, New York

Computational Biologist I

Job Posting Number: 11243

Allied Health – Pathology

New York,NY

June 1, 2017

Company Overview:

At Memorial Sloan Kettering (MSK), we’re not only changing the way we treat cancer, but also the way the world thinks about it. By working together and pushing forward with innovation and discovery, we’re driving excellence and improving outcomes.

For the 27th year, MSK has been named a top hospital for cancer by U.S. News & World Report. We are proud to be on Becker’s Healthcare list as one of the 150 Great Places to Work in Healthcare in 2016, as well as Glassdoor’s annual Employees’ Choice Awards 2016. We’re treating cancer, one patient at a time. Join us and make a difference every day.

Job Details:

The Molecular Diagnostics Laboratory within the Department of Pathology is applying next-generation sequencing techniques to characterize the spectrum of genetic mutations in patient tumors. These genomic data are guiding treatment decisions and the enrollment of patients onto clinical trials of novel targeted therapies.

The Computational Biologist within the Clinical Bioinformatics group will provide bioinformatics support in the development of next-generation sequencing applications to characterize the spectrum and clinical significance of genetic mutations in human tumors. He/she will develop new and utilize existing software and database systems to track experimental parameters, catalyze technology development, and analyze next-generation sequence data.

You Will:

  • Design, develop, and operate computational pipelines for the analysis of next-generation sequencing data.

  • Analyze data sets to discover and annotate cancer-causing genetic mutations in tumor specimens.

  • Perform manual review of genomic alterations discovered in cancer samples in clinical setting.

  • Communicate the genomic results with the MDS staff and attendings.

  • Evaluate performance of novel technology platforms and assays.

  • Work directly with research groups to analyze biomedical data and address scientific problems with bioinformatics techniques and tools and train researchers in the use of computational and bioinformatics tools

  • Develop, refine, and improve bioinformatics tools for interpretation of large genomic data sets.

  • Evaluate and test third party software packages.

  • Track specimen information, experimental and analysis parameters, performance metrics, and genomic results in databases

  • Manage and archive large data sets from next-generation sequencing experiments

  • Install and maintain software and data

  • Maintain detailed records of all analyses

  • Present results and progress updates at lab meetings and make presentations to experimental and scientific collaborators

  • Attend seminars, lectures, and training courses to learn new computational biology skills to remain up to date with the cancer genomics field and learn new programming languages or techniques as necessary

You Are:

  • Capable of building strong customer relationships and delivering customer-centric solutions

  • A good decision-maker, with proven success at making timely decisions that keep the organization moving forward

  • Able to work effectively in an environment notable for complex, sometimes contradictory information

  • Consistently achieving results, even under tough circumstances

  • Adept at planning and prioritizing work to meet commitments aligned with organizational

  • Adept at building partnerships and working collaboratively with others to meet shared objectives and goals

  • An effective communicator, capable of determining how best to reach different audiences and executing communications based on that understanding

  • Resilient in recovering from setbacks and skilled at finding detours around obstacles

  • Able to operate effectively, even when things are not clear or the way forward is not obvious

  • Adept at learning quickly, applying insights from past efforts to new situations

You Need:

MS in Bioinformatics or related with 0-2 years of related experience preferred. Bachelor’s Degree with 2-4 years of Next-generation sequencing and cancer genetics experience will be considered. This position requires cross-disciplinary and strong analytical skills as well as broad experience using computational methods, databases, software and hardware.


MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.

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